Can I take a natural supplement to treat my thyroid disease? It is most important to note that there is no special diet or vitamin that treats thyroid disease. Supplements do not have to be approved by the Federal Government before being sold to the public, and a prescription is not needed to buy them. You should always be cautious about claims that a product offers a “cure” but does not give specific information about how well their product works or claims that there are only positive results without side effects.  These supplements are rarely a part of standard care because there is no strong evidence that they are effective and safe. Because of possible risks, it is important to talk with a highly trained thyroid medical professional about any diets or supplements you are thinking about using.